Jekyll2022-12-08T17:37:55-08:00https://briankoepnick.com/feed.xmlHomeResearch scientist at the University of WashingtonBrian Koepnickbrian.koepnick@gmail.comProtein design partition tournament2018-08-30T00:00:00-07:002018-08-30T00:00:00-07:00https://briankoepnick.com/posts/2018/08/blog-post<p>Introducing a design tournament for Foldit players. Part three of a three-part blog series about the problem of protein design.</p>Brian Koepnickbrian.koepnick@gmail.comIntroducing a design tournament for Foldit players. Part three of a three-part blog series about the problem of protein design.Partition functions2018-08-27T00:00:00-07:002018-08-27T00:00:00-07:00https://briankoepnick.com/posts/2018/08/blog-post<p>A partition function describes the energy landscape of a protein. Part two of a three-part blog series about the problem of protein design.</p>Brian Koepnickbrian.koepnick@gmail.comA partition function describes the energy landscape of a protein. Part two of a three-part blog series about the problem of protein design.The problem of protein design2018-08-24T00:00:00-07:002018-08-24T00:00:00-07:00https://briankoepnick.com/posts/2018/08/blog-post<p>Discussion of energy landscapes, and how they complicate protein design. Part one of a three-part blog series about the protein design problem.</p>Brian Koepnickbrian.koepnick@gmail.comDiscussion of energy landscapes, and how they complicate protein design. Part one of a three-part blog series about the protein design problem.X-ray diffraction2017-05-30T00:00:00-07:002017-05-30T00:00:00-07:00https://briankoepnick.com/posts/2017/05/blog-post<p>X-ray diffraction experiments and the first crystal structure of a Foldit design.</p>Brian Koepnickbrian.koepnick@gmail.comX-ray diffraction experiments and the first crystal structure of a Foldit design.Protein crystallization2017-04-15T00:00:00-07:002017-04-15T00:00:00-07:00https://briankoepnick.com/posts/2017/04/blog-post<p>Growing a crystal of a Foldit player-designed protein, for crystal x-ray diffraction.</p>Brian Koepnickbrian.koepnick@gmail.comGrowing a crystal of a Foldit player-designed protein, for crystal x-ray diffraction.Foldit design update - Part 22017-03-01T00:00:00-08:002017-03-01T00:00:00-08:00https://briankoepnick.com/posts/2017/03/blog-post<p>Some promising lab results from recently-tested Foldit designs!</p>Brian Koepnickbrian.koepnick@gmail.comSome promising lab results from recently-tested Foldit designs!Foldit design update - Part 12017-02-28T00:00:00-08:002017-02-28T00:00:00-08:00https://briankoepnick.com/posts/2017/02/blog-post<p>Discussion of protein backbone quality and recent improvements in Foldit designs.</p>Brian Koepnickbrian.koepnick@gmail.comDiscussion of protein backbone quality and recent improvements in Foldit designs.Protein folding pathways2017-02-01T00:00:00-08:002017-02-01T00:00:00-08:00https://briankoepnick.com/posts/2017/02/blog-post<p>A Foldit player’s question about protein folding pathways.</p>Brian Koepnickbrian.koepnick@gmail.comA Foldit player’s question about protein folding pathways.More about the Blueprint Tool2017-01-30T00:00:00-08:002017-01-30T00:00:00-08:00https://briankoepnick.com/posts/2017/01/blog-post<p>More details about the recently-introduced Blueprint Panel in Foldit.</p>Brian Koepnickbrian.koepnick@gmail.comMore details about the recently-introduced Blueprint Panel in Foldit.Blueprint panel2016-10-27T00:00:00-07:002016-10-27T00:00:00-07:00https://briankoepnick.com/posts/2016/10/blog-post<p>Introducing a new tool to Foldit: the Blueprint Panel.</p>Brian Koepnickbrian.koepnick@gmail.comIntroducing a new tool to Foldit: the Blueprint Panel.